What actually happens during stem cell therapy for joint pain?
Medically reviewed by
Ajith Nair, M.D., board certified in Anesthesiology, Pain Medicine, Addiction Medicine, and Integrative Medicine
Last reviewed: July 2026
Stem cell therapy for joint pain is a procedure where cells are taken from your own body and placed into a painful joint or area of tissue. It is done in the office and is meant to be part of a broader pain management plan discussed with your physician.
The process usually has three parts. First, a sample is collected, often from your bone marrow or fat tissue, using a needle after the area is numbed. Second, that sample is prepared to concentrate the cells. Third, the concentrated material is injected into the target joint, frequently with imaging guidance so placement is precise.
If you feel soreness at the collection site or the injection site for a few days afterward, that is common and usually eases on its own. Most people return to light activity fairly soon and follow specific guidance from their physician on what to avoid.
It is fair to ask honest questions before you decide. Responses to this kind of treatment vary from person to person, and it is not right for everyone. Your physician can explain what is realistic for your specific joint, your imaging, and your history.
If you feel like you have tried injections and therapy without lasting relief, this is one option your specialist may discuss alongside others. It is not a replacement for a full evaluation.
Ask what the goal is in your case, how results would be measured, and what the alternatives are. A clear conversation about expectations, cost, and timing helps you decide whether this fits your situation rather than relying on general claims you read online.
At Kentuckiana Pain Specialists, stem cell therapy is provided under the care of Ajith Nair, M.D., at our Louisville and Radcliff, Kentucky clinics. Our phones are answered 24/7 at (502) 995-4004, and a consultation is the best way to find out what fits your situation.
This is general information, not medical advice. Whether a treatment is right for you is determined by a physician after an evaluation.